Toxicologic Pathology is pleased to announce the publication of a special 2021 issue focusing on Digital Pathology, Tissue Image Analysis, Artificial Intelligence, and Machine Learning in the context of Toxicologic Pathology and Drug Development. This collection of peer-reviewed original research articles and reviews will address multiple topics required for proficiency in these fields.

Internship in the Pharmaceutical or (Agro-) Chemical Industry:  Career in Toxicologic Pathology

The ESTP would like to promote young colleagues interested in veterinary pathology to discover toxicologic pathology. Therefore, we are happy to share the possibility to apply for internships in departments of pathology/preclinical development in the pharmaceutical and (agro-) chemical industry as well as in contract research laboratories (CRO's).

• An internship in the industry or a CRO aims to provide an introduction to the toxicological and experimental pathologist's daily duties, i.e. technical, scientific and communication aspects, and an understanding of how pathology data fits into drug/chemical development and safety. The intern might also have the possibility to actively contribute to a short project.

• An internship can for example include the following task and challenges: Exposure to systemic toxicology studies including slide evaluation and review together with an experienced pathologists, efficacy, mechanistic and investigative studies, and data handling experience (comprehensive pathology).

• Internships are offered for the following duration:
  • One-day job shadowing for veterinary students
  • Few weeks to several months for veterinary graduates or students currently in a pathology PhD training or residency program (Important: this type of internship is to date not registered as an official training accepted as resident training for the ECVP board preparation)..

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An official application for an internship generally includes a CV and a letter of motivation. Financial assistance cannot be provided by the ESTP but may be available from the respective company.

For any further information including contacts to laboratories willing to offer internships, please do not hesitate to contact us by email using  the contact tool at https://www.eurotoxpath.org/nextgen/index.php

Toxicologic Pathology is pleased to announce the publication of a special 2020 issue focusing on The Challenges of Inhaled Biotherapeutics. This peer-reviewed issue will bring together experts in the field of inhalation toxicology and pathology to provide an overview of the commonly encountered challenges associated with inhaled biologics. This issue will be forwarded by two white papers–the first addressing the pathological effects commonly seen with inhaled biologics and their implications for drug development, and the second addressing the toxicological and technical challenges associated with this route of delivery.

CLICK HERE for more information.

This call for papers seeks manuscripts from authors with experience in inhalation toxicology or the nonclinical development of inhaled biologics.

Toxicologic Pathology is pleased to announce the publication of a special 2020 issue focusing on Stem Cell-based Therapy Development. Rapid advances in stem cell biology have produced confusion and misinformation on the readiness of this field for clinical use in humans and animals. This peer reviewed special issue will emphasize the issues concerning cell therapies, exemplified but not limited to stem cell and related fields. Major focus will be safety assessment, issues complicating nonclinical  development of stem cell therapies, including study design, methods for evaluating histopathology findings, carcinogenicity evaluation, immune compatibility, and solutions to these issues to propel the field into the future therapies. This issue will explore concepts such as the fate of injected stem cells, teratoma formation and neoplasia, ectopic growths, use of autologous induced stem cells, use of stem cells in veterinary medicine and present state of the field. Also included will be issues of terminology and standardization of methods and nomenclature.

CLICK HERE for more information.

Call for proposals

The Biomedical Research Trust (BRET) is a charity which funds work to improve the care, use and replacement of animals in scientific research and increased public understanding of the role of animals in biomedical research.  Previous projects include schools speaker programmes, education for veterinary students, preparation of on line resources and travel bursaries.

We are inviting proposals for funding further work in two categories :

• Improved public education and understanding of the role of research using animals in the biological sciences, including medical advances
• to promote the use and development of 3Rs methods

Proposals should be brief, explaining how the work meets the aims of BRET, what you plan to do and a breakdown of costs.  Grants are usually up to £5000 but proposals for bigger projects may be considered.

If you would like to discuss an idea before submitting please contact us at bretenquiries@btinternet.com

BRET: Registered charity no 292366

The EPSR Co-ordinator would like to thank everyone who has registered by returning their EPSR Website Access T&Cs. If this is still on your to do list, the form is available in the EPSR section in the members only area of the website.

Also available is a filterable Excel spreadsheet containing the species, tissue and finding of each EPSR case for ease of identifying lesions of interest and we are now able to share the original case descriptions and discussions if any more detail is required on any of the cases in the EPSR archive.

I hope you agree that this is an exciting offering from the BSTP that will benefit all our members as well as enhancing future Webinars, Continuing Education Symposia and Annual Scientific Meetings, where we can also make use of this facility to share scanned slides. New cases for future use are always very welcome so if you have any interesting or unusual lesions or cases please contact the EPSR Co-ordinator via the BSTP Secretariat.