The 6th ESTP International Expert workshop will elaborate criteria for pathologists to assess adversity of thyroid follicular epithelial hypertrophy/ hyperplasia, taking into account the differentiation between direct and indirect mechanisms and their implication for risk assessment.
Based on practical examples and expert contributions, it will be the goal of this workshop to:
1. Summarize common mechanisms of thyroid follicular epithelial hypertrophy/hyperplasia and present example cases for direct and indirect modes of action
2. Discuss adversity considerations for thyroid follicular epithelial hypertrophy/hyperplasia, species differences/human relevance, and implications for classification as endocrine disrupting compound
3. Propose information requirements to support review and interpretation of thyroid follicular epithelial hypertrophy/hyperplasia with examples of information/testing strategies
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